The modulation of NMDA and AMPA/kainate receptors by tocotrienol-rich fraction and A-tocopherol in glutamate-induced injury of primary astrocytes

• Main Authors: Abedi, Zahra, Khaza’ai, Huzwah, Vidyadaran, Sharmili, Abd Mutalib, Mohd Sokhini
• Format: Article
• Language: English
• Published: MDPI 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/63489/1/The%20Modulation%20of%20NMDA%20and%20AMPAKainate.pdf; http://psasir.upm.edu.my/id/eprint/63489/

Astrocytes are known as structural and supporting cells in the central nervous system (CNS). Glutamate, as a main excitatory amino acid neurotransmitter in the mammalian central nervous system, can be excitotoxic, playing a key role in many chronic neurodegenerative diseases. The aim of the current...