Lipase-catalyzed synthesis of kojic acid derivative in bioreactors and the analysis of its depigmenting and antioxidant activities

• Main Authors: Lajis, Ahmad Firdaus, Hamid, Muhajir, Ahmad, Syahida, Ariff, Arbakariya
• Format: Article
• Language: English
• Published: M D P I AG 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/62314/1/Lipase-catalyzed%20synthesis%20of%20kojic%20acid%20derivative%20in%20bioreactors.pdf; http://psasir.upm.edu.my/id/eprint/62314/; https://www.mdpi.com/2079-9284/4/3/22

In this study, 7-O-kojic acid monopalmitate (7-O-KAP) was synthesized using palmitic acid and kojic acid where the yield and biological activities were analyzed. The highest yield of 7-O-KAP (43%) can be obtained at molar ratio of 1:1, enzyme loading of 5% (w/v), temperature of 70 °C, using immobili...