Histological analysis of anti-cancer drug loaded, targeted Mn:ZnS quantum dots in metastatic lesions of 4T1 challenged mice

• Main Authors: Bwatanglang, Ibrahim Birma, Mohammad, Faruq, Yusof, Nor Azah, Mohammed, Nurul Elyani, Abu, Nadiah, Alitheen, Noorjahan Banu, Abdullah, Jaafar, Hussein, Mohd Zubir, Abba, Yusuf, Nordin, Noraini, Zamberi, Nur Rizi
• Format: Article
• Language: English
• Published: Springer 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/62035/1/Histological%20analysis%20of%20anti-cancer%20drug%20.pdf; http://psasir.upm.edu.my/id/eprint/62035/; https://link.springer.com/article/10.1007%2Fs10856-017-5949-9

5-Fluororaucil (5-FU) as anti-cancer drug was reported to induce thymidine synthase (TS) overexpression and cancer cell resistance. To improve its therapeutic efficacy and selective targeting, here we developed a targeted delivery system mediated by the active ligand-folate receptor chemistry to del...