Evaluation of in vitro efficacy of docetaxel-loaded calcium carbonate aragonite nanoparticles (DTX-CaCO3NP) on 4T1 mouse breast cancer cell line

• Main Authors: Ibrahim Hammadi, Nahidah, Abba, Yusuf, Mohd Noor, Mohd Hezmee, Abdul Razak, Intan Shameha, Kura, Aminu Umar, Abu Bakar @ Zakaria, Md Zuki
• Format: Article
• Language: English
• Published: Springer-Verlag 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/61786/1/Evaluation%20of%20in%20vitro%20efficacy%20of%20docetaxel-loaded%20calcium%20carbonate%20aragonite%20nanoparticles%20.pdf; http://psasir.upm.edu.my/id/eprint/61786/; https://link.springer.com/article/10.1007/s11626-017-0197-3

Cockle shell-derived calcium carbonate nanoparticles have shown promising potentials as slow drug-releasing compounds in cancer chemotherapy. In this study, we evaluated the in vitro efficacy of docetaxel (DTX)-loaded CaCO3NP on 4T1 cell line. This was achieved by evaluating the following: cytotoxic...