Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug

• Main Authors: Krishnan, Poorani, Rajan, Mariappan, Kumari, Sharmilah, Syed, Sakinah, Priya, Sivan Padma, Fatin Amira, Danjuma, Lawal, Mok, Pooi Ling, Fakurazi, Sharida, Arulselvan, Palanisamy, Higuchi, Akon, Arumugam, Ramitha, Alarfaj, Abdullah A., Munusamy, Murugan A., Hamat, Rukman Awang, Benelli, Giovanni, Murugan, Kadarkarai, Kumar, S. Suresh
• Format: Article
• Language: English
• Published: Nature Publishing Group 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/61681/1/Efciency%20of%20newly%20formulated.pdf; http://psasir.upm.edu.my/id/eprint/61681/

Camptothecin (CPT) is an anti-cancer drug that effectively treats various cancers, including colon cancer. However, poor solubility and other drawbacks have restricted its chemotherapeutic potential. To overcome these restrictions, CPT was encapsulated in CEF (cyclodextrin-EDTA-FE3O4), a composite n...