Comparing the calcium bioavailability from two types of nano-sized enriched milk using in-vivo assay

• Main Authors: Erfanian, Arezoo, Rasti, Babak, Abdul Manap, Yazid
• Format: Article
• Language: English
• Published: Elsevier 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/61172/1/Comparing%20the%20calcium%20bioavailability%20from%20two%20types%20of%20nano-sized%20enriched%20milk%20using%20in-vivo%20assay.pdf; http://psasir.upm.edu.my/id/eprint/61172/; https://ac.els-cdn.com/S0308814616311499/1-s2.0-S0308814616311499-main.pdf?_tid=ce67a233-185e-4790-b185-288a5302e609&acdnat=1551172388_672c266ca28685dfcf763283311268a4

Calcium bioavailability from two types of enriched (calcium citrate and calcium carbonate) milks homogenized to a nano-sized particle distribution has been studied among 48 female Sprauge-dawley rats. Skim milk powder was enriched with some essential nutrients (Inulin, DHA & EPA, vitamins B6, K1, and D3) as enhancers of calcium bioavailability according to recommended dietary allowances of the West European and North American. Ovariectomized and ovariectomized-osteoporosis rats were used as a menopause and menopause-osteoporosis model, respectively. Although, nano-sized enriched milk powders had the greatest calcium bioavailability among the groups, but bioavailability of nano-sized calcium carbonate-enriched-milk was significantly (P<0.05) better than nano-sized calcium citrate-enriched-milk. Moreover, the trends were similar for bone calcium, strength and morphology. Therefore, based on the current results the calcium carbonate nano-sized enriched milk could be an effective enriched milk powder in ovariectomized-osteoporosis and ovariectomized rats as a model of menopause-osteoporosis and menopause women.