Improvement of isolated caprine islet survival and functionality in vitro by enhancing of PDX1 gene expression

• Main Authors: Hani, Homayoun, Allaudin, Zeenathul Nazariah, Mohd Lila, Mohd Azmi, Sarsaifi, Kazhal, Rasouli, Mina, Tam, Yew Joon, Tengku Ibrahim, Tengku Azmi, Othman, Abas Mazni
• Format: Article
• Language: English
• Published: John Wiley & Sons 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/59623/1/Improvement%20of%20isolated%20caprine%20islet%20survival%20and%20functionality%20in%20vitro%20by%20enhancing%20of%20PDX1%20gene%20expression.pdf; http://psasir.upm.edu.my/id/eprint/59623/; http://onlinelibrary.wiley.com/wol1/doi/10.1111/xen.12302/abstract

Background: Dead islets replaced with viable islets are a promising offer to restore normal insulin production to a person with diabetes. The main reason for establishing a new islet source for transplantation is the insufficiency of human donor pancreas while using xenogeneic islets perhaps assists...