Patched-1 and smoothened, a hedgehog receptor and signal transducer are highly expressed in diffuse large B-cell lymphoma

• Main Authors: Azman, Siti Nur Lina, Hussin, Huzlinda, Md Said, Salmiah, Alias, Zanariah, Abdullah, Maizaton Atmadini
• Format: Article
• Language: English
• Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/58278/1/2017082916032701_MJMHS_Vol13_No2_2017_-_0048_-_p1-6_5th_proof_FINAL.pdf; http://psasir.upm.edu.my/id/eprint/58278/; http://www.medic.upm.edu.my/upload/dokumen/2017082916032701_MJMHS_Vol13_No2_2017_-_0048_-_p1-6_5th_proof_FINAL.pdf

Introduction: The Hedgehog (Hh) signalling pathway is a developmental signalling pathway involved in normal mammalian developmental and homeostasis of adult renewable tissues. In most adult tissues, this pathway remains silent and previous studies have shown that constitutive activation of Hedgehog...