Combination of cisplatin and bromelain exerts synergistic cytotoxic effects against breast cancer cell line MDA-MB-231 in vitro

• Main Authors: Mat Pauzi, Ahmad Zaim, Yeap, Swee Keong, Abu, Nadiah, Lim, Kian Lam, Omar, Abdul Rahman, Abd. Aziz, Suraini, Leow, Adam Thean Chor, Subramani, Tamilselvan, Tan, Soon Guan, Mohammed Alitheen, Noorjahan Banu
• Format: Article
• Language: English
• Published: BioMed Central 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/55309/1/Combination%20of%20cisplatin%20and%20bromelain.pdf; http://psasir.upm.edu.my/id/eprint/55309/; https://cmjournal.biomedcentral.com/articles/10.1186/s13020-016-0118-5

Background: Bromelain, which is a cysteine endopeptidase commonly found in pineapple stems, has been investigated as a potential anti-cancer agent for the treatment of breast cancer. However, information pertaining to the effects of combining bromelain with existing chemotherapeutic drugs remains sc...