Antiplasmodial and chloroquine chemosensitizing and resistance reversal effects of coumarin derivatives against Plasmodium falciparum 3D7 and K1

• Main Authors: O. Ibraheem, Zaid, Abd Majid, Roslaini, M. S., Hasidah, Md Noor, Sabariah, Rahi, Sattar, Basir, Rusliza
• Format: Article
• Language: English
• Published: Malaysian Society of Parasitology and Tropical Medicine 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/55095/1/Antiplasmodial%20and%20chloroquine%20chemosensitizing%20and%20resistance%20reversal%20effects%20of%20coumarin%20derivatives%20against%20Plasmodium%20falciparum%203D7%20and%20K1.pdf; http://psasir.upm.edu.my/id/eprint/55095/; http://www.msptm.org/journal.html

Background Emergence of chloroquine (CQ) resistance among different strains of Plasmodium falciparum is the worst incident that has ever faced the dedicated efforts to eradicate malaria. The main cause of CQ resistance is over-activity of the pumping mechanism that ousts CQ outside the DV. This urge...