Human mesenchymal stromal cells modulate T-cell immune response via transcriptomic regulation

• Main Authors: Vellasamy, Shalini, Tong, Chih Kong, Azhar, Nur Atiqah, Kodiappan, Radha, Chan, Soon Choy, Veerakumarasivam, Abhi, Ramasamy, Rajesh
• Format: Article
• Language: English
• Published: Elsevier 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/54461/1/Human%20mesenchymal%20stromal%20cells%20modulate%20T-cell%20immune%20response%20via%20transcriptomic%20regulation.pdf; http://psasir.upm.edu.my/id/eprint/54461/; https://www.sciencedirect.com/science/article/pii/S1465324916304510?via%3Dihub

Background aims: Mesenchymal stromal cells (MSCs) have been identified as pan-immunosuppressant in various in vitro and in vivo inflammatory models. Although the immunosuppressive activity of MSCs has been explored in various contexts, the precise molecular signaling pathways that govern inhibitory...