New indolizidine alkaloids from psychrophilic yeast Glyciozyma antarctica PI12

• Main Authors: Rosandy, Andi Rifki, Nadarajah, Wickneswary, Abu Bakar, Muntaz, Cheah, Yoke Kqueen, Mohd. Said, Mohd. Ikram, Al Muqarrabun, Laode Muhammad Ramadhan, Khalid, Rozida
• Format: Article
• Language: English
• Published: Malaysian Analytical Sciences Society 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/53373/1/New%20indolizidine%20alkaloids%20from%20psychrophilic%20yeast%20Glyciozyma%20antarctica%20PI12.pdf; http://psasir.upm.edu.my/id/eprint/53373/; http://www.ukm.my/mjas/mjas2017/

Two alkaloid compounds: namely 3-(1-aminoethyl)tetrahydro-1H-pyrrolo[1,2-d][1,2,4]oxadiazine-1,4(3H)-dione (1) and tetrahydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,3(4H)-dione (2) was isolated from Glyciozyma antarctica (PI12), a psychrophilic yeast. The isolated compounds were isolated by Radial Chromatography and Thin Layer Chromatography techniques. The chemical structures were elucidated by Ultraviolet-visible, Infrared, Nuclear Magnetic Resonance and Mass Spectroscopy.