Cytotoxic effect of ethanol extract of microalga, Chaetoceros calcitrans, and its mechanisms in inducing apoptosis in human breast cancer cell line

• Main Authors: Nigjeh, Siyamak Ebrahimi, Md. Yusoff, Fatimah, Mohammed Alitheen, Noorjahan Banu, Pirozyan, Mehdi Rasoli, Yeap, Swee Keong, Omar, Abdul Rahman
• Format: Article
• Language: English
• Published: Hindawi Publishing Corporation 2013
• Online Access: http://psasir.upm.edu.my/id/eprint/52001/1/52001.pdf; http://psasir.upm.edu.my/id/eprint/52001/; https://www.hindawi.com/journals/bmri/2013/783690/abs/

Marine microalgae have been prominently featured in cancer research. Here, we examined cytotoxic effect and apoptosis mechanism of crude ethanol extracts of an indigenous microalga, Chaetoceros calcitrans (UPMAAHU10) on human breast cell lines. MCF-7 was more sensitive than MCF-10A with IC50 value o...