Evaluation of the cytotoxic and genotoxic effects of goniothalamin in leukemic cell lines

• Main Authors: Rajab, Nor Fadilah, Abd. Hamid, Zariyantey, Hassan, Hunaizah, Ali, Abdul Manaf, Din, Laily, Inayat Hussain, Salmaan Hussain
• Format: Article
• Language: English
• Published: The Japanese Environmental Mutagen Society 2005
• Online Access: http://psasir.upm.edu.my/id/eprint/48591/1/Evaluation%20of%20the%20cytotoxic%20and%20genotoxic%20effects%20of%20goniothalamin%20in%20leukemic%20cell%20lines.pdf; http://psasir.upm.edu.my/id/eprint/48591/; https://www.jstage.jst.go.jp/article/jems/27/3/27_3_161/_article

The cytotoxic and genotoxic effects of goniothalamin, a plant styryllactone, were evaluated using the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay and the Alkaline Comet assay respectively in human leukemic cell lines. Following 72 h of treatment, the IC50 values of g...