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Synthesis of a DNA-targeting nickel (II) complex with testosterone thiosemicarbazone which exhibits selective cytotoxicity towards human prostate cancer cells (LNCaP)

Testosterone thiosemicarbazone, L and its nickel (II) complex 1 were synthesized and characterized by using FTIR, CHN, (1)H NMR, and X-ray crystallography. X-ray diffraction study confirmed the formation of L from condensation of testosterone and thiosemicarbazide. Mononuclear complex 1 is coordinat...

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Bibliographic Details
Main Authors: Mok, Piew Heng, Sinniah, Saravana Kumar, Wuen, Yew Teoh, Kae, Shin Sim, Seik, Weng Ng, Cheah, Yoke Kqueen, Kong, Wai Tan
Format: Article
Language:English
Published: Elsevier 2015
Online Access:http://psasir.upm.edu.my/id/eprint/46466/1/Synthesis%20of%20a%20DNA-targeting%20nickel%20%28II%29%20complex%20with%20testosterone%20thiosemicarbazone%20which%20exhibits%20selective%20cytotoxicity%20towards%20human%20prostate%20cancer%20cells%20%28LNCaP%29.pdf
http://psasir.upm.edu.my/id/eprint/46466/
http://www.elsevier.com/locate/issn/13861425
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http://psasir.upm.edu.my/id/eprint/46466/1/Synthesis%20of%20a%20DNA-targeting%20nickel%20%28II%29%20complex%20with%20testosterone%20thiosemicarbazone%20which%20exhibits%20selective%20cytotoxicity%20towards%20human%20prostate%20cancer%20cells%20%28LNCaP%29.pdf
http://psasir.upm.edu.my/id/eprint/46466/
http://www.elsevier.com/locate/issn/13861425

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