Prevalence of the CYP2D6*10 (C100T), *4 (G1846A), and *14 (G1758A) alleles among Iranians of different ethnicities

• Main Authors: Bagheri, Ali, Kamalidehghan, Behnam, Haghshenas, Maryam, Azadfar, Parisa, Akbari, Leila, Sangtarash, Mohammad Hossein, Vejdandoust, Faramarz, Ahmadipour, Fatemeh, Meng, Goh Yong, Houshmand, Massoud
• 格式: Article
• 语言: English
• 出版: Dove Medical Press 2015
• 在线阅读: http://psasir.upm.edu.my/id/eprint/45992/1/Prevalence%20of%20the%20CYP2D6%2010%20%28C100T%29%2C%204%20%28G1846A%29%20and%2014%20%28G1758A%29%20alleles%20in%20Iranian%20populations%20of%20different%20ethnicities.pdf; http://psasir.upm.edu.my/id/eprint/45992/; https://www.dovepress.com/prevalence-of-the-cyp2d610nbspc100t-4nbspg1846a-and-14nbspg1758a-allel-peer-reviewed-fulltext-article-DDDT

The presence of polymorphisms in the CYP2D6 gene may modulate enzyme level and activity, thereby affecting individual responses to pharmacological treatment. Here, we compared the prevalence of the CYP2D6*10, *4, and 14* alleles in an Iranian population of different ethnicities with those of other p...