Pluripotency maintenance of amniotic fluid-derived stem cells cultured on biomaterials

• Main Authors: Wang, Pin Yu, Lee, Henry Hsin Chung, Higuchi, Akon, Ling, Qing Dong, Lin, Hong Ren, Li, Hsin Fen, Kumar, S. Suresh, Chang, Yung, Alarfaj, Abdullah A., Munusamy, Murugan A., Chen, Da Chung, Hsu, Shih Tien, Wang, Han Chow, Hsiao, Hung Yi, Wu, Gwo Jang
• Format: Article
• Language: English
• Published: Royal Society of Chemistry 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/45885/1/STEM.pdf; http://psasir.upm.edu.my/id/eprint/45885/; https://pubs.rsc.org/en/content/articlelanding/2015/tb/c5tb00447k#!divAbstract

The stem cell fates of pluripotency and differentiation are regulated by not only soluble biological cues but also insoluble biochemical cues (i.e., extracellular matrix (ECM)) and the physical cues of cell culture biomaterials (i.e., elasticity). We investigated the maintenance of pluripotency and...