Physical cues of cell culture materials lead the direction of differentiation lineages of pluripotent stem cells

• Main Authors: Higuchi, Akon, Ling, Qing Dong, Kumar, S. Suresh, Yung, Chang, Alarfaj, Abdullah A., Munusamy, Murugan A., Murugan, Kadarkarai, Hsu, Shih Tien, Umezawa, Akihiro
• Format: Article
• Language: English
• Published: Royal Society of Chemistry 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/45850/1/CELL.pdf; http://psasir.upm.edu.my/id/eprint/45850/; https://pubs.rsc.org/en/content/articlelanding/2015/tb/c5tb01276g#!divAbstract

Both human pluripotent stem cells (hPSCs) from embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) have the potential ability to differentiate into many different cell types originating from all three germ layers. This review discusses physical cues from natural and synthetic bi...