A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity

• Main Authors: Khairul Ikram, Nur Kusaira, Durrant, Jacob D., Muchtaridi, M., Zalaludin, Ayunni Salihah, Purwitasari, Neny, Mohamed, Nornisah, Abdul Rahim, Aisyah Saad, Chan, Kit Lam, Mohd Yahaya, Normi, Abd Rahman, Noorsaadah, Amaro, Rommie E., A. Wahab, Habibah
• Format: Article
• Language: English
• Published: ACS Publications 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/43627/1/123.pdf; http://psasir.upm.edu.my/id/eprint/43627/; http://pubs.acs.org/doi/10.1021/ci500405g

Recent outbreaks of highly pathogenic and occasional drug-resistant influenza strains have highlighted the need to develop novel anti-influenza therapeutics. Here, we report computational and experimental efforts to identify influenza neuraminidase inhibitors from among the 3000 natural compounds in...