Identification of α°-thalassaemia (–SEA) using an enzyme-linked immunosorbent assay (ELISA) for embryonic zeta-globin chain detection – a preliminary study

• Main Authors: Tan, Mary Anne Jin Ai, George, Elizabeth, Lim, E. J., Zakaria, Z., Hassan, R., Wee, Y. C., Tan, K. L.
• Format: Article
• Language: English
• Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2006
• Online Access: http://psasir.upm.edu.my/id/eprint/41187/1/Identification%20of%20%CE%B1%C2%B0.pdf; http://psasir.upm.edu.my/id/eprint/41187/; http://www.medic.upm.edu.my/dokumen/FKUSK1_MJMHS_2006V02N2_OP04.pdf

Objectives: This study aimed to evaluate the UBI MAGIWELTM ζ-GLOBIN ELISA Kit for the presumptive diagnosis of αo-thalassaemia. The ELISA results obtained were confirmed by molecular characterisation of αo-thalassaemia using a Duplex-PCR. Methods: Routine peripheral blood counts and red cell indices...