Nasal carriage of Staphylococcus aureus among healthy adults
Background and Purpose: Data on the carriage rate and antibiotic sensitivity pattern of Staphylococcus aureus strains prevalent in the community are not available for many developing countries including Malaysia. To estimate the extent of community S. aureus transmission, in particular methicillin-r...
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Elsevier
2006
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Online Access: | http://psasir.upm.edu.my/id/eprint/40054/1/Nasal%20carriage%20of%20Staphylococcus%20aureus%20among%20healthy%20adults.pdf http://psasir.upm.edu.my/id/eprint/40054/ http://www.ejmii.com/issue_abstract.php?code=PDT4b0e741317ad8 |
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my.upm.eprints.400542015-08-27T04:09:22Z http://psasir.upm.edu.my/id/eprint/40054/ Nasal carriage of Staphylococcus aureus among healthy adults Chong, Seng Choi Chow, Suet Yin Abu Bakar, Afra Sakewi, Zamberi Naing, Nyi Nyi Jamal, Farida Othman, Norlijah Background and Purpose: Data on the carriage rate and antibiotic sensitivity pattern of Staphylococcus aureus strains prevalent in the community are not available for many developing countries including Malaysia. To estimate the extent of community S. aureus transmission, in particular methicillin-resistant S. aureus (MRSA), the prevalence of S. aureus nasal colonization in a population of healthy adults was determined. Factors associated with S. aureus nasal carriage and antibiotic sensitivity patterns of the isolates were also analyzed. Methods: A cross-sectional study involving 346 adults was conducted. Nasal swabs were examined for the presence of S. aureus. Epidemiological information concerning risk factors for nasal carriage was also obtained. Antibiotic susceptibility testing was performed using the disk diffusion method according to the National Committee for Clinical Laboratory Standards guidelines. MRSA strains isolated were further subjected to pulse-field gel electrophoresis analysis. Results: The prevalence of S. aureus nasal carriage was 23.4%. The findings also revealed that ex-smokers (95% confidence interval [CI] 1.08-6.32, p=0.033) and oral contraceptive users (95% CI 1.12-21.67, p=0.035) were more likely to harbor S. aureus. One person was colonized with MRSA, which was different from the hospital strain. Conclusion: MRSA nasal colonization was found to be low outside of the health care environment. Smokers and oral contraceptive users have high nasal carrier rates. Elsevier 2006-12 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/40054/1/Nasal%20carriage%20of%20Staphylococcus%20aureus%20among%20healthy%20adults.pdf Chong, Seng Choi and Chow, Suet Yin and Abu Bakar, Afra and Sakewi, Zamberi and Naing, Nyi Nyi and Jamal, Farida and Othman, Norlijah (2006) Nasal carriage of Staphylococcus aureus among healthy adults. Journal of Microbiology, Immunology and Infection, 39 (6). pp. 458-464. ISSN 1684-1182; ESSN: 1995-9133 http://www.ejmii.com/issue_abstract.php?code=PDT4b0e741317ad8 |
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Background and Purpose: Data on the carriage rate and antibiotic sensitivity pattern of Staphylococcus aureus strains prevalent in the community are not available for many developing countries including Malaysia. To estimate the extent of community S. aureus transmission, in particular methicillin-resistant S. aureus (MRSA), the prevalence of S. aureus nasal colonization in a population of healthy adults was determined. Factors associated with S. aureus nasal carriage and antibiotic sensitivity patterns of the isolates were also analyzed. Methods: A cross-sectional study involving 346 adults was conducted. Nasal swabs were examined for the presence of S. aureus. Epidemiological information concerning risk factors for nasal carriage was also obtained. Antibiotic susceptibility testing was performed using the disk diffusion method according to the National Committee for Clinical Laboratory Standards guidelines. MRSA strains isolated were further subjected to pulse-field gel electrophoresis analysis. Results: The prevalence of S. aureus nasal carriage was 23.4%. The findings also revealed that ex-smokers (95% confidence interval [CI] 1.08-6.32, p=0.033) and oral contraceptive users (95% CI 1.12-21.67, p=0.035) were more likely to harbor S. aureus. One person was colonized with MRSA, which was different from the hospital strain. Conclusion: MRSA nasal colonization was found to be low outside of the health care environment. Smokers and oral contraceptive users have high nasal carrier rates. |
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Article |
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Chong, Seng Choi Chow, Suet Yin Abu Bakar, Afra Sakewi, Zamberi Naing, Nyi Nyi Jamal, Farida Othman, Norlijah |
spellingShingle |
Chong, Seng Choi Chow, Suet Yin Abu Bakar, Afra Sakewi, Zamberi Naing, Nyi Nyi Jamal, Farida Othman, Norlijah Nasal carriage of Staphylococcus aureus among healthy adults |
author_facet |
Chong, Seng Choi Chow, Suet Yin Abu Bakar, Afra Sakewi, Zamberi Naing, Nyi Nyi Jamal, Farida Othman, Norlijah |
author_sort |
Chong, Seng Choi |
title |
Nasal carriage of Staphylococcus aureus among healthy adults |
title_short |
Nasal carriage of Staphylococcus aureus among healthy adults |
title_full |
Nasal carriage of Staphylococcus aureus among healthy adults |
title_fullStr |
Nasal carriage of Staphylococcus aureus among healthy adults |
title_full_unstemmed |
Nasal carriage of Staphylococcus aureus among healthy adults |
title_sort |
nasal carriage of staphylococcus aureus among healthy adults |
publisher |
Elsevier |
publishDate |
2006 |
url |
http://psasir.upm.edu.my/id/eprint/40054/1/Nasal%20carriage%20of%20Staphylococcus%20aureus%20among%20healthy%20adults.pdf http://psasir.upm.edu.my/id/eprint/40054/ http://www.ejmii.com/issue_abstract.php?code=PDT4b0e741317ad8 |
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13.19449 |