An influenza A vaccine based on the extracellular domain of matrix 2 protein protects BALB/C mice against H1N1 and H3N2

• Main Authors: Ong, Hui Kian, Yong, Chean Yeah, Tan, Wen Siang, Yeap, Swee Keong, Omar, Abdul Rahman, Abdul Razak, Mariatulqabtiah, Ho, Kok Lian
• Format: Article
• Language: English
• Published: MDPI 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/38287/1/38287.pdf; http://psasir.upm.edu.my/id/eprint/38287/; https://www.mdpi.com/2076-393X/7/3/91

Current seasonal influenza A virus (IAV) vaccines are strain-specific and require annual reconstitution to accommodate the viral mutations. Mismatches between the vaccines and circulating strains often lead to high morbidity. Hence, development of a universal influenza A vaccine targeting all IAV st...