Development of a biocompatible nanodelivery system for tuberculosis drugs based on isoniazid-Mg/Al layered double hydroxide

• Main Authors: Saifullah, Bullo, Arulselvan, Palanisamy, El Zowalaty, Mohamed Ezzat, Fakurazi, Sharida, Webster, Thomas J., Geilich, Benjamin M., Hussein, Mohd Zobir
• Format: Article
• Language: English
• Published: Dove Medical Press 2014
• Online Access: http://psasir.upm.edu.my/id/eprint/37053/1/Development%20of%20a%20biocompatible%20nanodelivery%20system%20for%20tuberculosis%20drugs%20based%20on%20isoniazid.pdf; http://psasir.upm.edu.my/id/eprint/37053/; http://www.dovepress.com/development-of-a-biocompatible-nanodelivery-system-for-tuberculosis-dr-peer-reviewed-article-IJN

The primary challenge in finding a treatment for tuberculosis (TB) is patient non-compliance to treatment due to long treatment duration, high dosing frequency, and adverse effects of anti-TB drugs. This study reports on the development of a nanodelivery system that intercalates the anti-TB drug iso...