Acute toxicity and metabolomics analysis of hypocholesterolemic effect of Mentha piperita aqueous extract in Wistar rats

• Main Authors: Johari, Nor Zaini, Ismail, Intan Safinar, Sulaiman, Mohd Roslan, Abas, Faridah, Shaari, Khozirah
• Format: Article
• Language: English
• Published: Healthy-Synergies Publications 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/36325/1/Acute%20toxicity%20and%20metabolomics%20analysis%20of%20hypocholesterolemic%20effect%20of%20Mentha%20piperita%20aqueous%20extract%20in%20Wistar%20rats.pdf; http://psasir.upm.edu.my/id/eprint/36325/; http://www.ijarnp.org/index.php/ijarnp/article/view/269

The oral acute toxicity of the aqueous peppermint extract (APE) was assessed and the bio and/or chemo markers for hypocholesterolemic activity of APE were identified through metabolomics approach. No mortality resulted from the present oral acute toxicity study in which the histological changes obse...