A classical genetic solution to enhance the biosynthesis of anticancer phytochemicals in Andrographis paniculata nees

• Main Authors: Valdiani, Alireza, Talei, Daryush, Tan, Soon Guan, Abdul Kadir, Mihdzar, Mahmood, Maziah, Yusop, Mohd Rafii, Sagineedu, Sreenivasa Rao
• Format: Article
• Language: English
• Published: Public Library of Science 2014
• Online Access: http://psasir.upm.edu.my/id/eprint/36128/1/A%20classical%20genetic%20solution%20to%20enhance%20the%20biosynthesis%20of%20anticancer%20phytochemicals%20in%20Andrographis%20paniculata%20nees.pdf; http://psasir.upm.edu.my/id/eprint/36128/; http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087034

Andrographolides, the diterpene lactones, are major bioactive phytochemicals which could be found in different parts of the medicinal herb Andrographis paniculata. A number of such compounds namely andrographolide (AG), neoandrographolide (NAG), and 14-deoxy-11,12-didehydroandrographolide (DDAG) hav...