A case report of signet-ring cell carcinoma of the colon in a 21 year old man

• Main Authors: Mohammad Nor, Ahmad Muhsin, Lee, Y. L., Mat Arif, Nor Aishah, Abdul Wahab, Md Hamsan, Nallusamy, Kumareson, Hussin, Huzlinda
• Format: Article
• Language: English
• Published: PBS Journals 2014
• Online Access: http://psasir.upm.edu.my/id/eprint/36125/1/A%20case%20report%20of%20signet.pdf; http://psasir.upm.edu.my/id/eprint/36125/; http://pbsjournals.com/ajmcs/archview.php?id=166&jid=Case%20Report

Signet-ring cell carcinoma of the colon is a rare and aggressive form of colonic cancer which is associated with a very poor prognosis. Various studies have shown that the majority of these cases are encountered in late adulthood. We report a case of a 21-year old man who presented with abdominal pain and altered bowel habit. Colonoscopy examination showed a circumferential growth causing a narrowed bowel lumen at the descending colon. Both barium enema and computed tomography findings showed a long segment malignant stricture at the descending colon. Tissue biopsy indicated features of signet-ring cell carcinoma. He underwent segmental resection of the cancerous lesion with end colostomy when he presented to us with an obstructed and advanced malignant stricture of the descending colon.