The differential metabolite profiles of acute lymphoblastic leukaemic patients treated with 6-mercaptopurine using untargeted metabolomics approach

• Main Authors: Bannur, Zakaria, Teh, Lay Kek, Hennesy, T., Wan Rosli, Wan Rosalina, Mohamad, Norsarwany, Nasir, Ariffin, Ankathil, Ravindran, Zakaria, Zainul Amiruddin, Baba, Aziz, Salleh, Mohd Zaki
• Format: Article
• Published: Elsevier 2014
• Online Access: http://psasir.upm.edu.my/id/eprint/35655/; http://www.sciencedirect.com/science/article/pii/S0009912014000745

Background Acute lymphoblastic leukaemia (ALL) has posed challenges to the clinician due to variable patients' responses and late diagnosis. With the advance in metabolomics, early detection and personalised treatment are possible. Methods Metabolomic profile of 21 ALL patients treated with...