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Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells

Newcastle disease virus (NDV) is an enveloped single stranded RNA virus that causes deadly infection to over 250 species of birds, comprising domestic and wild-type, thus resulting in substantial economic loss to poultry industry across the globe. NDV possesses several distinctive properties that ma...

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Main Authors: Ahmed, Ismaila, Ahmad, Umar, Othman, Fauziah, Yong, Yoke Keong
Format: Article
Published: International Journal of Pharmaceutical and Clinical Research 2014
Online Access:http://psasir.upm.edu.my/id/eprint/34667/
http://ijpcr.com/volume6issue3/
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spelling my.upm.eprints.346672015-12-18T00:17:33Z http://psasir.upm.edu.my/id/eprint/34667/ Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells Ahmed, Ismaila Ahmad, Umar Othman, Fauziah Yong, Yoke Keong Newcastle disease virus (NDV) is an enveloped single stranded RNA virus that causes deadly infection to over 250 species of birds, comprising domestic and wild-type, thus resulting in substantial economic loss to poultry industry across the globe. NDV possesses several distinctive properties that make it an outstanding anti-cancer agent. In humans it is reported to have oncolytic and immune-stimulatory effects, precisely replicates in tumour cells while sparing normal cells and causes oncolysis. Although NDV has been extensively studied by researchers there is still need for a vigorous research on its potential use as a new treatment modality to cancer patients through a known process termed viroimmunotherapy. This paper deals with an overview of the research which has been carried out worldwide in the use of immune-stimulatory properties of NDV as an anti-cancer agent. International Journal of Pharmaceutical and Clinical Research 2014 Article PeerReviewed Ahmed, Ismaila and Ahmad, Umar and Othman, Fauziah and Yong, Yoke Keong (2014) Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells. International Journal of Pharmaceutical an d Clinical Research, 6 (3). pp. 196-200. ISSN 0975-1556 http://ijpcr.com/volume6issue3/
institution Universiti Putra Malaysia
building UPM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Putra Malaysia
content_source UPM Institutional Repository
url_provider http://psasir.upm.edu.my/
description Newcastle disease virus (NDV) is an enveloped single stranded RNA virus that causes deadly infection to over 250 species of birds, comprising domestic and wild-type, thus resulting in substantial economic loss to poultry industry across the globe. NDV possesses several distinctive properties that make it an outstanding anti-cancer agent. In humans it is reported to have oncolytic and immune-stimulatory effects, precisely replicates in tumour cells while sparing normal cells and causes oncolysis. Although NDV has been extensively studied by researchers there is still need for a vigorous research on its potential use as a new treatment modality to cancer patients through a known process termed viroimmunotherapy. This paper deals with an overview of the research which has been carried out worldwide in the use of immune-stimulatory properties of NDV as an anti-cancer agent.
format Article
author Ahmed, Ismaila
Ahmad, Umar
Othman, Fauziah
Yong, Yoke Keong
spellingShingle Ahmed, Ismaila
Ahmad, Umar
Othman, Fauziah
Yong, Yoke Keong
Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells
author_facet Ahmed, Ismaila
Ahmad, Umar
Othman, Fauziah
Yong, Yoke Keong
author_sort Ahmed, Ismaila
title Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells
title_short Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells
title_full Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells
title_fullStr Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells
title_full_unstemmed Non-specific immunostimulatory capacity of Newcastle disease virus (NDV) and suppression of breast cancer cells
title_sort non-specific immunostimulatory capacity of newcastle disease virus (ndv) and suppression of breast cancer cells
publisher International Journal of Pharmaceutical and Clinical Research
publishDate 2014
url http://psasir.upm.edu.my/id/eprint/34667/
http://ijpcr.com/volume6issue3/
_version_ 1643831222665740288
score 13.188404

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