Label-free dengue detection utilizing PNA/DNA hybridization based on the aggregation process of unmodified gold nanoparticles

• Main Authors: Abdul Rahman, Samsulida, Saadun, Rafidah, Azmi, Nur Ellina, Ariffin, Nurhayati, Abdullah, Jaafar, Yusof, Nor Azah, Sidek, Hamidah, Hajian, Reza
• Format: Article
• Published: Hindawi Publishing Corporation 2014
• Online Access: http://psasir.upm.edu.my/id/eprint/34341/; http://dx.doi.org/10.1155/2014/839286

A label-free optical detection method based on PNA/DNA hybridization using unmodified gold nanoparticles (AuNPs) for dengue virus detection has been successfully developed. In this study, no immobilization method is involved and the hybridization of PNA/DNA occurs directly in solution. Unmodified Au...