Biomarkers in cancer: an overview
Traditional tumour markers such as carcinoembryonic antigen (CEA) that have been used for screening gastrointestinal neoplasia for many years are not specific. However, these markers are useful after diagnosis to monitor progress of the disease and recurrence. New biomarkers are constantly being dev...
Saved in:
Main Author: | |
---|---|
Format: | Article |
Published: |
Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
2008
|
Online Access: | http://psasir.upm.edu.my/id/eprint/32884/ |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
my.upm.eprints.32884 |
---|---|
record_format |
eprints |
spelling |
my.upm.eprints.328842015-10-07T06:49:58Z http://psasir.upm.edu.my/id/eprint/32884/ Biomarkers in cancer: an overview Seow, Heng Fong Traditional tumour markers such as carcinoembryonic antigen (CEA) that have been used for screening gastrointestinal neoplasia for many years are not specific. However, these markers are useful after diagnosis to monitor progress of the disease and recurrence. New biomarkers are constantly being developed to identify individuals with risk of cancer for early detection, to determine prognosis, to detect recurrence, to predict drug responses and to monitor response to treatment. There are several issues involved in the discovery of biomarkers and their development for clinical applications. This article provides a basic overview of the classes of biomarkers, the current status of molecular profiling and discusses the opportunities as well as challenges ahead to improve biomarker development. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2008-01 Article PeerReviewed Seow, Heng Fong (2008) Biomarkers in cancer: an overview. Malaysian Journal of Medicine and Health Sciences, 4 (1). pp. 23-32. ISSN 1675-8544 |
institution |
Universiti Putra Malaysia |
building |
UPM Library |
collection |
Institutional Repository |
continent |
Asia |
country |
Malaysia |
content_provider |
Universiti Putra Malaysia |
content_source |
UPM Institutional Repository |
url_provider |
http://psasir.upm.edu.my/ |
description |
Traditional tumour markers such as carcinoembryonic antigen (CEA) that have been used for screening gastrointestinal neoplasia for many years are not specific. However, these markers are useful after diagnosis to monitor progress of the disease and recurrence. New biomarkers are constantly being developed to identify individuals with risk of cancer for early detection, to determine prognosis, to detect recurrence, to predict drug responses and to monitor response to treatment. There are several issues involved in the discovery of biomarkers and their development for clinical applications. This article provides a basic overview of the classes of biomarkers, the current status of molecular profiling and discusses the opportunities as well as challenges ahead to improve biomarker development. |
format |
Article |
author |
Seow, Heng Fong |
spellingShingle |
Seow, Heng Fong Biomarkers in cancer: an overview |
author_facet |
Seow, Heng Fong |
author_sort |
Seow, Heng Fong |
title |
Biomarkers in cancer: an overview |
title_short |
Biomarkers in cancer: an overview |
title_full |
Biomarkers in cancer: an overview |
title_fullStr |
Biomarkers in cancer: an overview |
title_full_unstemmed |
Biomarkers in cancer: an overview |
title_sort |
biomarkers in cancer: an overview |
publisher |
Faculty of Medicine and Health Sciences, Universiti Putra Malaysia |
publishDate |
2008 |
url |
http://psasir.upm.edu.my/id/eprint/32884/ |
_version_ |
1643830720337018880 |
score |
13.160551 |