Thymoquinone prevents β-amyloid neurotoxicity in primary cultured cerebellar granule neurons

• Main Authors: Ismail, Norsharina, Ismail, Maznah, Mazlan, Musalmah, Abd Latiff, Latiffah, Imam, Mustapha Umar, Iqbal, Shahid, Azmi, Nur Hanisah, Abd Ghafar, Siti Aisyah, Kim, Wei Chan
• Format: Article
• Language: English
• Published: Springer 2013
• Online Access: http://psasir.upm.edu.my/id/eprint/30729/1/Thymoquinone%20prevents%20%CE%B2.pdf; http://psasir.upm.edu.my/id/eprint/30729/

Thymoquinone (TQ), a bioactive constituent of Nigella sativa Linn (N. sativa) has demonstrated several neuropharmacological attributes. In the present study, the neuroprotective properties of TQ were investigated by studying its anti-apoptotic potential to diminish β-amyloid peptide 1–40 sequence (A...