Protection of astaxanthin in astaxanthin nanodispersions using additional antioxidants

• Main Authors: Anarjan, Navideh, Nehdi, Imededdine Arbi, Tan, Chin Ping
• Format: Article
• Language: English
• Published: MDPI 2013
• Online Access: http://psasir.upm.edu.my/id/eprint/30463/1/Protection%20of%20astaxanthin%20in%20astaxanthin%20nanodispersions%20using%20additional%20antioxidants.pdf; http://psasir.upm.edu.my/id/eprint/30463/; http://dx.doi.org/10.3390/molecules18077699

The protective effects of α-tocopherol and ascorbic acid on astaxanthin in astaxanthin nanodispersions produced via a solvent-diffusion technique and stabilized by a three-component stabilizer system, were studied either individually or in combination by using response surface methodology. Generally, both α-tocopherol and ascorbic acid could retard the astaxanthin degradation in astaxanthin nanodispersions. The results showed that the using α-tocopherol and ascorbic acid can be more efficient in increasing the chemical stability of nanodispersions in comparison to using them individually. Using a response surface methodology (RSM) response optimizer, it was seen that addition of ascorbic acid (ascorbic acid/astaxanthin w/w) and α-tocopherol (α-tocopherol/astaxanthin w/w) in proportions of 0.4 and 0.6, respectively, would give the maximum chemical stability to the studied astaxanthin nanodispersions.