Synthesis of bisindolylmethanes and their cytotoxicity properties.

• Main Authors: Mohan Naidu, Kalla Reddi, Khalivulla, Shaik Ibrahim, Syed Rasheed,, Fakurazi, Sharida, Arulselvan, Palanisamy, Lasekan, Olasegun, Abas, Faridah
• Format: Article
• Language: English; English
• Published: MDPI Publishing 2013
• Online Access: http://psasir.upm.edu.my/id/eprint/30448/1/Synthesis%20of%20bisindolylmethanes%20and%20their%20cytotoxicity%20properties.pdf; http://psasir.upm.edu.my/id/eprint/30448/; http://www.mdpi.com/1422-0067/14/1/1843

Polymer supported dichlorophosphate (PEG-OPOCl2) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compo...