A phenylbutenoid dimer, cis-3-(3′,4′-dimethoxyphenyl)-4-[(E)-3′′′,4′′′-dimethoxystyryl] cyclohex-1-ene, exhibits apoptogenic properties in T-acute lymphoblastic leukemia cells via induction of p53-independent mitochondrial signalling pathway

The current study was designed to evaluate the in vitro cytotoxicity effect of a phenylbutenoid dimer, cis-3-(3′,4′-dimethoxyphenyl)-4-[(E)- 3‴,4‴-dimethoxystyryl]cyclohex-1-ene (ZC-B11) isolated from the rhizome of Zingiber cassumunar on various cancer cell line, and normal human blood mononuclear...

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Bibliographic Details
Main Authors: Anasamy, Theebaa, Abdul, Ahmad Bustamam, Sukari, Mohd Aspollah, Abdelwahab, Siddig Ibrahim, Mohan, Syam, Kamalidehghan, Behnam, Azid, Mohd Zulkhairi, Muhammad Nadzri, Nabilah, Andas, A. Reenaa Joys, Beng, Ng Kuan, A. Hadi, A. Hamid, Rahman, Heshu Sulaiman
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:http://psasir.upm.edu.my/id/eprint/30040/1/A%20phenylbutenoid%20dimer.pdf
http://psasir.upm.edu.my/id/eprint/30040/
http://dx.doi.org/10.1155/2013/939810
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