An assessment of three noncommercial DNA extraction methods from dried blood spots for beta-thalassaemia mutation identification.

• Main Authors: Kartipan, S. N., George, Elizabeth, Sathar, Jameela, Lim, Wai Feng, Teh, Lai Kuan, Lee, T. Y., Chin, V. K., Lai, Mei I.
• Format: Article
• Language: English; English
• Published: Wiley 2011
• Online Access: http://psasir.upm.edu.my/id/eprint/24521/1/An%20assessment%20of%20three%20noncommercial%20DNA%20extraction%20methods%20from%20dried%20blood%20spots%20for%20beta.pdf; http://psasir.upm.edu.my/id/eprint/24521/

Introduction: Dried blood spots (DBS) are currently the recommended sample collection method for newborn screening programmes in America. Early diagnosis of beta-thalassaemia screening is essential as it provides an added advantage especially in sickle cell disease. Beta-thalassaemia frequency is hi...