Deep sequencing analysis of the developing mouse brain reveals a novel microRNA.

• Main Authors: Ling, King Hwa, Brautigan, Peter J., Hahn, Christopher N., Daish, Tasman, Rayner, John R., Cheah, Pike See, Raison, Joy M., Piltz, Sandra, Mann, Jeffrey R., Mattiske, Deidre M., Thomas, Paul Q., Adelson, David L., Scott, Hamish S.
• Format: Article
• Language: English; English
• Published: BioMed Central 2011
• Online Access: http://psasir.upm.edu.my/id/eprint/24428/1/Deep%20sequencing%20analysis%20of%20the%20developing%20mouse%20brain%20reveals%20a%20novel%20microRNA.pdf; http://psasir.upm.edu.my/id/eprint/24428/; http://www.biomedcentral.com/bmcgenomics

Background: MicroRNAs (miRNAs) are small non-coding RNAs that can exert multilevel inhibition/repression at a post-transcriptional or protein synthesis level during disease or development. Characterisation of miRNAs in adult mammalian brains by deep sequencing has been reported previously. However,...