A genome wide study of copy number variation associated with nasopharyngeal carcinoma in Malaysian Chinese identifies CNVs at 11q14.3 and 6p21.3 as candidate loci

• Main Authors: Low, Joyce Siew Yong, Chin, Yoon Ming, Mushiroda, Taisei, Kubo, Michiaki, Govindasamy, Gopala Krishnan, Pua, Kin Choo, Yap, Yoke Yeow, Yap, Lee Fah, Subramaniam, Selva Kumar, Ong, Cheng Ai, Tan, Tee Yong, Khoo, Alan Soo Beng, The Malaysian NPC Study Group,, Ng, Ching Ching
• Format: Article
• Language: English
• Published: Public Library of Science 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/17534/1/journal.pone.0145774.PDF; http://psasir.upm.edu.my/id/eprint/17534/

Background: Nasopharyngeal carcinoma (NPC) is a neoplasm of the epithelial lining of the nasopharynx. Despite various reports linking genomic variants to NPC predisposition, very few reports were done on copy number variations (CNV). CNV is an inherent structural variation that has been found to be...