Synthesis and biological activity of oxadiazole and triazolothiadiazole derivatives as tyrosinase inhibitors
A series of 16 oxadiazole and triazolothiadiazole derivatives were designed, synthesized and evaluated as mushroom tyrosinase inhibitors. Five derivatives were found to display high inhibition on the tyrosinase activity ranging from 0.87 to 1.49 lM. Compound 5 exhibited highest tyrosinase inhibitor...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/16919/1/Synthesis%20and%20biological%20activity%20of%20oxadiazole%20and%20triazolothiadiazole%20derivatives%20as%20tyrosinase%20inhibitors.pdf http://psasir.upm.edu.my/id/eprint/16919/ |
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