Successful transfer of plasmid DNA into in vitro cells transfected with an inorganic plasmidMg/Al-LDH nanobiocomposite material as a vector for gene expression

• Main Authors: Masarudin, Mas Jaffri, Yusoff, Khatijah, Abdul Rahim, Raha, Hussein, Mohd. Zobir
• Format: Article
• Language: English; English
• Published: IOI Publishing 2009
• Online Access: http://psasir.upm.edu.my/id/eprint/16887/1/Successful%20transfer%20of%20plasmid%20DNA%20into%20in%20vitro%20cells%20transfected%20with%20an%20inorganic%20plasmidMg.pdf; http://psasir.upm.edu.my/id/eprint/16887/

The delivery of a full plasmid, encoding the green fluorescent protein gene into African monkey kidney (Vero3) cells, was successfully achieved using nanobiocomposites based on layered double hydroxides. This demonstrated the potential of using the system as an alternative DNA delivery vector. Inte...