Novel approach of vaccination against Brucella abortus 544 based on a combination of fusion proteins, human serum albumin and brucella abortus Lipopolysaccharides.

• Main Authors: Pakzad, Iraj, Rezaee, Abbas, Rasaee, Mohammad Javad, Hosseini, Ahmad Zavaran, Tabbaraee, Bahman, Ghafurian, Sobhan, Abdulamir, Ahmed Sahib, Abu Bakar, Fatimah, Mohammad, Raftari
• Format: Article
• Language: English; English
• Published: Asian Network for Scientific Information (ANSINET) 2010
• Online Access: http://psasir.upm.edu.my/id/eprint/15842/1/Novel%20approach%20of%20vaccination%20against%20Brucella%20abortus%20544%20based%20on%20a%20combination%20of%20fusion%20proteins.pdf; http://psasir.upm.edu.my/id/eprint/15842/; http://scialert.net/abstract/?doi=jbs.2010.767.772

Lipopolysaccharide (LPS) of Brucella abortus is an essential component for developing the subunit vaccine against brucellosis. B. abortus LPS was extracted by n-butanol, purified by ultracentrifugation and detoxified by alkaline treatment. Pyrogenicity and toxicity of B. abortus LPS and detoxified–L...