Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.
Chromatin morphologies in human breast cancer cells treated with an anti-cancer agent are analyzed at their early stage of programmed cell death or apoptosis. The gray-level images of nuclear chromatin are modelled as random fields. We used two-dimensional isotropic generalized Cauchy field to chara...
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my.upm.eprints.156722015-10-23T06:27:55Z http://psasir.upm.edu.my/id/eprint/15672/ Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. Muniandy, Sithi V. Stanslas, Johnson Chromatin morphologies in human breast cancer cells treated with an anti-cancer agent are analyzed at their early stage of programmed cell death or apoptosis. The gray-level images of nuclear chromatin are modelled as random fields. We used two-dimensional isotropic generalized Cauchy field to characterize local self-similarity and global long-range dependence behaviors in the image spatial data. Generalized Cauchy field allows the description of fractal behavior inferred from fractal dimension and the long-range dependence inferred from correlation exponent to be carried out independently. We demonstrated the usefulness of locally self-similar random fields with long-range dependence for modelling chromatin condensation. Elsevier 2008-10 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/15672/1/Modelling%20of%20chromatin%20morphologies%20in%20breast%20cancer%20cells%20undergoing%20apoptosis%20using%20generalized%20Cauchy%20field.pdf Muniandy, Sithi V. and Stanslas, Johnson (2008) Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. Computerized Medical Imaging and Graphics , 32 (7). pp. 631-637. ISSN 0895-6111; ESSN:1879-0771 http://www.elsevier.com 10.1016/j.compmedimag.2008.07.003 English |
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Chromatin morphologies in human breast cancer cells treated with an anti-cancer agent are analyzed at their early stage of programmed cell death or apoptosis. The gray-level images of nuclear chromatin are modelled as random fields. We used two-dimensional isotropic generalized Cauchy field to characterize local self-similarity and global long-range dependence behaviors in the image spatial data. Generalized Cauchy field allows the description of fractal behavior inferred from fractal dimension and the long-range dependence inferred from correlation exponent to be carried out independently. We demonstrated the usefulness of locally self-similar random fields with long-range dependence for modelling chromatin condensation. |
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Article |
author |
Muniandy, Sithi V. Stanslas, Johnson |
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Muniandy, Sithi V. Stanslas, Johnson Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. |
author_facet |
Muniandy, Sithi V. Stanslas, Johnson |
author_sort |
Muniandy, Sithi V. |
title |
Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. |
title_short |
Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. |
title_full |
Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. |
title_fullStr |
Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. |
title_full_unstemmed |
Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. |
title_sort |
modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized cauchy field. |
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Elsevier |
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2008 |
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http://psasir.upm.edu.my/id/eprint/15672/1/Modelling%20of%20chromatin%20morphologies%20in%20breast%20cancer%20cells%20undergoing%20apoptosis%20using%20generalized%20Cauchy%20field.pdf http://psasir.upm.edu.my/id/eprint/15672/ http://www.elsevier.com |
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