Immunohistochemical detection of phospho-Akt, phospho-BAD, HER2 and oestrogen receptors α and β in Malaysian breast cancer patients

• Main Authors: Seow, Heng Fong, Yip, Wai Kien, Loh, Hui Woon, Ithnin, Hairuszah, Por, Patricia, Muhammad, Rohaizak
• Format: Article
• Language: English
• Published: Springer 2010
• Online Access: http://psasir.upm.edu.my/id/eprint/15099/1/Immunohistochemical%20detection%20of%20phospho-Akt%2C%20phospho-BAD%2C%20HER2%20and%20oestrogen%20receptors%20%CE%B1%20and%20%CE%B2%20in%20Malaysian%20breast%20cancer%20patients.pdf; http://psasir.upm.edu.my/id/eprint/15099/; http://link.springer.com/article/10.1007%2Fs12253-009-9216-3

Activation of Akt signaling pathway has been documented in various human malignancies, including breast carcinoma. The objective of this study is to determine the incidence of Akt phosphorylation in breast tumours and its relationship with expression of ER-α, ER-β, HER2, Ki-67 and phosphorylated Bcl...