Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis

• Main Authors: Tan, Bee Ling, Mohd Esa, Norhaizan, Ky, Huynh, Rahman, Heshu Sulaiman, Yeap, Swee Keong, Hamzah, Hazilawati, Karim, Roselina
• Format: Article
• Language: English
• Published: BioMed Central 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/15081/1/15081.pdf; http://psasir.upm.edu.my/id/eprint/15081/; https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0730-4

Background: Brewers’ rice, is locally known as temukut, is a mixture of broken rice, rice bran, and rice germ. The current study is an extension of our previous work, which demonstrated that water extract of brewers’ rice (WBR) induced apoptosis in human colorectal cancer (HT-29) cells. We also iden...