Expression of Notch-1 receptor and its ligands Jagged-1 and Delta-1 in amoeboid microglia in postnatal rat brain and murine BV-2 cells.

• Main Authors: Cao, Qiong, Lu, Jia, Kaur, Charanjit, Sivakumar, Viswanathan, Li, Fan, Cheah , Pike See, Dheen, S. Thameem, Ling, Eng Ang
• Format: Article
• Language: English; English
• Published: Wiley-Blackwell 2008
• Online Access: http://psasir.upm.edu.my/id/eprint/14673/1/Expression%20of%20Notch.pdf; http://psasir.upm.edu.my/id/eprint/14673/

Notch-1 receptor signaling pathway is involved in neuronal and glial differentiation. Its involvement in microglial functions, however, has remained elusive. This study reports the localization of Notch-1 receptor immunoreactivity in the amoeboid microglial cells (AMC) in the postnatal rat brain. By...