Cytotoxic effect of 2’, 3’-epoxy isocapnolactone and 8-hydroxyisocapnolactone-2’3’-diol isolated from Micromelum minutum (G.Forst.) Wight and Arn. in human T-lymphocyte leukemia CEM-SS cells

• Main Authors: Tan, Kar Ban, Mohammed Alitheen, Noorjahan Banu, Yeap, Swee Keong, Ali, Abdul Manaf, Rahmani, Mawardi
• Format: Article
• Language: English
• Published: Academic Journals 2009
• Online Access: http://psasir.upm.edu.my/id/eprint/13858/1/13858.pdf; http://psasir.upm.edu.my/id/eprint/13858/; http://www.academicjournals.org/journal/AJB/article-abstract/F48A1C29321

2’,3’-Epoxyisocapnolactone and 8-hydroxyisocapnolactone-2’,3’-diol are two bioactive compounds isolated from the leaves of Micromelum minutum. In this study, the induction of apoptosis by 2’,3’-epoxyisocapnolactone and 8-hydroxyisocapnolactone-2’,3’-diol on CEM-SS cells were investigated. The cytoto...