Bidesmosidic oleanane saponins from Xerospermum noronhianum

• Main Authors: Tan, Pei Jean, Shaari, Khozirah, Paetz, Christian, Ismail, Intan Safinar, Abas, Faridah, Lajis, Md. Nordin, Ahmad, Viqar Uddin
• Format: Article
• Language: English
• Published: Verlag Helvetica Chimica Acta 2009
• Online Access: http://psasir.upm.edu.my/id/eprint/13391/1/Bidesmosidic%20oleanane%20saponins%20from%20Xerospermum%20noronhianum.pdf; http://psasir.upm.edu.my/id/eprint/13391/

Three new oleanane-type triterpenoid saponins, 3-O-(α-L-rhamnopyranosyl(12)-β-D-fucopyranosyl)-28-O-{[α-L-rhamnopyranosyl(12)] [β-D-fucopyranosyl(16)]-β-D-glucopyranosyl} oleanolic acid (1), 3-O-[α-L-rhamnopyranosyl(13)-β-D-fucopyranosyl]-28-O-[α-L-rhamnopyranosyl(14)-β-D-glucopyranosyl] oleanolic acid (2), and 3-O-{α-L-rhamnopyranosyl(12)-[3′,4′-diacetoxy-β-D-fucopyranosyl]}-28-O-[α-L-rhamnopyranosyl(12)-β-D-glucopyranosyl] oleanolic acid (3) have been isolated from the stems of Xerospermum noronhianum. The structures of the saponins were determined as a series of bidesmosidic oleanane saponins based on spectral evidence. The anticholinesterase activity of the saponins 1–3 was also evaluated.