Artificial neural network modeling studies to predict the yield of enzymatic synthesis of betulinic acid ester

• Main Authors: Moghaddam, Mansour Ghaffari, Ahmad @ Amat, Faujan, Basri, Mahiran, Abdul Rahman, Mohd Basyaruddin
• Format: Article
• Language: English
• Published: Pontificia Universidad Catolica de Valparaiso 2010
• Online Access: http://psasir.upm.edu.my/id/eprint/13278/1/Artificial%20neural%20network%20modeling%20studies%20to%20predict%20the%20yield%20of%20enzymatic%20synthesis%20of%20betulinic%20acid%20ester.pdf; http://psasir.upm.edu.my/id/eprint/13278/; http://www.ejbiotechnology.info/index.php/ejbiotechnology/article/view/v13n3-9

3β-O-phthalic ester of betulinic acid was synthesized from reaction of betulinic acid and phthalic anhydride using lipase as biocatalyst. This ester has clinical potential as an anticancer agent. In this study, artificial neural network (ANN) analysis of Candida antarctica lipase (Novozym 435) -cata...