Optimization of medium formulations for biomass vaccine production of gdhA derivative Pasteurella multocida B:2 using statistical experimental design

• 主要な著者: Oslan, Siti Nur Hazwani, Loo, Jiun Shen, Mohamad, Rosfarizan, Bejo, Siti Khairani, Saad, Mohd Zamri
• フォーマット: 論文
• 言語: English
• 出版事項: Elsevier 2025
• オンライン･アクセス: http://psasir.upm.edu.my/id/eprint/115934/1/115934.pdf; http://psasir.upm.edu.my/id/eprint/115934/; https://linkinghub.elsevier.com/retrieve/pii/S1878818125000179

The glutamate dehydrogenase (gdhA) gene of a pathogenic Pasteurella multocida B:2 was successfully inactivated to create an attenuated strain as a vaccine candidate against hemorrhagic septicemia (HS) in ruminants. This study presents a novel approach to optimizing the medium formulation for high-th...