Aberrant blood brain barrier dynamics in cerebral small vessel disease - a review of associations, pathomechanisms and therapeutic potentials

• Main Authors: Zul Ramli, Sayyidah Maryamul Azra’, Abdul Hamid, Hafizah, Che Mohd Nassir, Che Mohd Nasril, A Rahaman, Siti Nurulnabila, Mehat, Muhammad Zulfadli, Kumar, Jaya, Lee, Si-Yuen, Mustapha, Muzaimi
• Format: Article
• Language: English
• Published: OAE Publishing Inc. 2024
• Online Access: http://psasir.upm.edu.my/id/eprint/115758/1/115758.pdf; http://psasir.upm.edu.my/id/eprint/115758/; https://www.oaepublish.com/articles/2574-1209.2024.22

This review explores the pivotal role of the blood-brain barrier (BBB) in maintaining central nervous system (CNS) homeostasis and its dynamic involvement in the pathogenesis of cerebral small vessel disease (CSVD), i.e., the major precursor of age-related neurodegenerative diseases such as vascular...