Inhibition of macromolecular synthesis in cultured macrophages by Pseudomonas pseudomallei exotoxin
Pseudornonas pseudomallei exotoxin was found to be a potent inhibitor of protein and DNA synthesis in cultured macrophages. Inhibition of DNA synthesis occurred at toxin concentrations as low as 1–2 μg/ml and inhibition of 3H~thymidine uptake was almost complete at concentrations of 8 μgjml or more....
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
John Wiley & Sons
1989
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| Online Access: | http://psasir.upm.edu.my/id/eprint/115693/1/115693.pdf http://psasir.upm.edu.my/id/eprint/115693/ https://onlinelibrary.wiley.com/doi/10.1111/j.1348-0421.1989.tb00967.x |
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